The purpose of the study was to analyze and compare the job satisfaction with twenty dimensions of male and female higher secondary school heads in Khyber Pakhtunkhwa. A total of 108 higher secondary school heads were selected from eleven districts as sample through multi-stage sampling technique in which 66 were male and 42 were female. The study was descriptive in nature and therefore, quantitative and survey research design was used. A modified version of standardized tool "Minnesota Satisfaction Questionnaire (MSQ)" was used for data collection. Raw data was collected, organized, classified, tabulated, coded and analyzed. For statistical analysis, proper descriptive statistics i.e., mean, standard deviation, percentage and inferential statistics i.e., t-test were employed through statistical software SPSS version 17. The findings showed that on the whole, higher secondary school heads were found satisfied intrinsically and extrinsically with their job position except five dimensions i.e. ability utilization, supervision (HR), supervision (technical), school policies and working conditions. Furthermore, no significant difference was found between male and female higher secondary school heads' satisfaction with regard to intrinsic and extrinsic dimensions of their job position except ability utilization and compensation. Based on findings, it was suggested that Ministry of Education should formulate effective and productive policies favorable to the workforce of education department. Constructive and productive steps should be taken by the Ministry of Education, Government of Khyber Pakhtunkhwa and school administrators to ensure conducive working conditions by providing basic facilities and special budget. Technically supervision on the behalf of the district education officers may be conducted by ADEOs etc. who may properly train for dealing with public and handling the issues wisely.