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ERIC Number: EJ1109108
Record Type: Journal
Publication Date: 2015-Dec
Pages: 17
Abstractor: As Provided
ISSN: ISSN-1759-2879
Get Real in Individual Participant Data (IPD) Meta-Analysis: A Review of the Methodology
Debray, Thomas P. A.; Moons, Karel G. M.; van Valkenhoef, Gert; Efthimiou, Orestis; Hummel, Noemi; Groenwold, Rolf H. H.; Reitsma, Johannes B.
Research Synthesis Methods, v6 n4 p293-309 Dec 2015
Individual participant data (IPD) meta-analysis is an increasingly used approach for synthesizing and investigating treatment effect estimates. Over the past few years, numerous methods for conducting an IPD meta-analysis (IPD-MA) have been proposed, often making different assumptions and modeling choices while addressing a similar research question. We conducted a literature review to provide an overview of methods for performing an IPD-MA using evidence from clinical trials or non-randomized studies when investigating treatment efficacy. With this review, we aim to assist researchers in choosing the appropriate methods and provide recommendations on their implementation when planning and conducting an IPD-MA. [The authors wrote this article on behalf of the GetReal methods review group.]
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Publication Type: Journal Articles; Information Analyses; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A