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ERIC Number: EJ1108995
Record Type: Journal
Publication Date: 2013-Sep
Pages: 14
Abstractor: As Provided
ISSN: ISSN-1759-2879
Survey of the Methods and Reporting Practices in Published Meta-analyses of Test Performance: 1987 to 2009
Dahabreh, Issa J.; Chung, Mei; Kitsios, Georgios D.; Terasawa, Teruhiko; Raman, Gowri; Tatsioni, Athina; Tobar, Annette; Lau, Joseph; Trikalinos, Thomas A.; Schmid, Christopher H.
Research Synthesis Methods, v4 n3 p242-255 Sep 2013
We performed a survey of meta-analyses of test performance to describe the evolution in their methods and reporting. Studies were identified through MEDLINE (1966-2009), reference lists, and relevant reviews. We extracted information on clinical topics, literature review methods, quality assessment, and statistical analyses. We reviewed 760 publications reporting meta-analyses of test performance, published between 1987 and 2009. Eligible reviews included a median of 18 primary studies that were used in quantitative analyses. Most common clinical areas were cardiovascular disease (21%) and oncology (25%); most common test categories were imaging (44%) and biomarker tests (28%). Assessment of verification and spectrum bias, blinding, prospective study design, and consecutive patient recruitment became more common over time (p < 0.001 comparing reviews published through 2004 vs 2005 onwards). These changes coincided with the increasing use of checklists to guide assessment of methodological quality. Heterogeneity tests were used in 58% of meta-analyses; subgroup or regression analyses were used in 57%. Random effects models were employed in 57% of meta-analyses (38% through 2004 vs 72% 2004-onwards; p < 0.001). Use of bivariate models of sensitivity and specificity increased in recent years (21% in 2008-2009 vs 7% in earlier years; p < 0.001). Methods employed in meta-analyses of test performance have improved with the introduction of quality assessment checklists and the development of more sophisticated statistical methods.
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Publication Type: Journal Articles; Information Analyses; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: Agency for Healthcare Research and Quality (AHRQ) (DHHS/PHS)
Authoring Institution: N/A
Grant or Contract Numbers: R01HS013328; HHSA290200710055I