This study test a specified model of information technology (IT) preparedness as antecedent of pre-service teachers' self efficacy, perceived usefulness, and intention toward IT use for teaching in Nigeria. Survey method was employed for prosecuting the study. The participants of the study comprise of 200 pre-service teachers studying Mathematics education in one of the Nigerian universities. The instrument used for data collection was adapted and subjected to validation and reliability check. A factor analysis revealed four constructs and their reliability indexes were 0.73, 0.87, 0.90 and 0.91 Cronbach alpha respectively. The data of the study was subjected to factor analysis, confirmatory factor analysis and finally fitting the specified model of the study with AMOS 20 statistical package. The finding showed that IT preparedness positively predicts pre-service teachers' IT self-efficacy, perceived usefulness and in-turn predicts their intention towards use of IT for future classroom practice. Based on this finding, the study suggests among others the holistic deployment of IT resources among teacher educator for pre-service teacher training.