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ERIC Number: EJ1103842
Record Type: Journal
Publication Date: 2016-Jul
Pages: 6
Abstractor: As Provided
ISSN: ISSN-0162-3257
Brief Report: Sensory Reactivity in Children with Phelan-McDermid Syndrome
Mieses, A. M.; Tavassoli, T.; Li, E.; Soorya, L.; Lurie, S.; Wang, A. T.; Siper, P. M.; Kolevzon, A.
Journal of Autism and Developmental Disorders, v46 n7 p2508-2513 Jul 2016
Phelan-McDermid syndrome (PMS), a monogenic form of autism spectrum disorder (ASD), results from deletion or mutation of the "SHANK3" gene. Atypical sensory reactivity is now included in the diagnostic criteria for ASD. Examining the sensory phenotype in monogenic forms of ASD, such as PMS, may help identify underlying mechanisms of sensory reactivity. Using the Short Sensory Profile, the current study compared sensory reactivity in 24 children with PMS to 61 children with idiopathic ASD (iASD). Results suggest that children with PMS show "more" low energy/weak symptoms and "less" sensory sensitivity as compared to children with iASD. This study is the first to demonstrate differences in sensory reactivity between children with PMS and iASD, helping to refine the PMS phenotype.
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A