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ERIC Number: EJ1103818
Record Type: Journal
Publication Date: 2016-Jul
Pages: 13
Abstractor: As Provided
ISSN: ISSN-0162-3257
Classifying Autism Spectrum Disorders by ADI-R: Subtypes or Severity Gradient?
Cholemkery, Hannah; Medda, Juliane; Lempp, Thomas; Freitag, Christine M.
Journal of Autism and Developmental Disorders, v46 n7 p2327-2339 Jul 2016
To reduce phenotypic heterogeneity of Autism spectrum disorders (ASD) and add to the current diagnostic discussion this study aimed at identifying clinically meaningful ASD subgroups. Cluster analyses were used to describe empirically derived groups based on the Autism Diagnostic Interview-revised (ADI-R) in a large sample of n = 463 individuals with ASD aged 3-21. Three clusters were observed. Most severely affected individuals regarding all core symptoms were allocated to cluster 2. Cluster 3 comprised moderate symptom severity of social communication impairments (SCI) and less stereotyped repetitive behavior (RRB). Minor SCI and relatively more RRB characterized cluster 1. This study offers support for both, a symptom profile, and a gradient model of ASD within the spectrum due to the sample included.
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A