In order to increase students' awareness for and comfort with mathematical modeling of biological processes, and increase their understanding of diffusion, the following lab was developed for use in 100-level, majors/non-majors biology and neuroscience courses. The activity begins with generation of a data set that uses coin-flips to replicate movement of dye molecules at an interface of a permeable gel. The class results are then collapsed into a single data set that is used to predict the movement of real dye molecules over time, which are then measured by students in a "wet-lab" activity.