The purpose of this study is to determine the factors effected calculus learning outcome of the student. This study was conducted with 176 respondents, which were selected randomly. The data were obtained by questionnaire, and then analyzed by using multiple regressions, and correlation, at level of a = 0.05. The findings showed there is the significantly correlation between the basic mathematics competence of the learners, learners' attitude towards calculus, students' assessment on lecturers' teaching competence with learners' achievement on calculus separately and simultaneously.