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ERIC Number: EJ1101552
Record Type: Journal
Publication Date: 2016-May
Pages: 4
Abstractor: As Provided
ISSN: ISSN-0021-9584
A Hydrazine-Free Wolff-Kishner Reaction Suitable for an Undergraduate Laboratory
Cranwell, Philippa B.; Russell, Andrew T.
Journal of Chemical Education, v93 n5 p949-952 May 2016
A Wolff-Kishner reaction that does not require hydrazine has been developed. The reaction sequence has two steps: formation of a carbomethoxyhydrazone from methyl hydrazinocarboxylate and acetophenone, then decomposition of this intermediate by treatment with potassium hydroxide in triethylene glycol. Purification is by filtration through a plug of silica encased in the barrel of a plastic syringe. The reaction sequence can be completed within a day-long laboratory class (8 h).
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Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education; Postsecondary Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A