Case method teaching is a method of instruction that can improve the cognitive learning process. This method is used extensively in face-to-face classes. However, when it is applied to a distance education class in an online asynchronous environment, learning outcomes may differ. This article reports on a study that compares the use of case method teaching in face-to-face and online asynchronous environments. Four hypotheses on student performance were proposed. Correlation analysis supported all of the hypotheses. Other interesting findings regarding online learning also were reported as a result of the data analysis. Overall, an online asynchronous environment can promote students' participation in certain cases; however, cognitive learning gains do not seem to be as high as in the face-to-face environment. With distance education becoming more prevalent, this is a rich area for future research.