In this research, for an effective learning of concepts in the scope of functional groups in organic chemistry, it has been developed as "Organic Chemistry Taboo (OrCheTaboo)" which is an educational activity by the researchers. The aim of this study is to analyze the effect of the game OrCheTaboo on learning of concepts related to functional groups. The study group of the research consists of 62 students who took the Organic Chemistry Laboratory Course in the spring term and they enrolled in the Department of Secondary Science and Mathematics Education of a Faculty of Education at a state university in Turkey. Quasi-experimental design with pretest-posttest control group has been used. As a result, the game OrCheTaboo gives the opportunity to be in conceptual development processes like describing the terms to the students, identifying from the other terms or establishing its similar characteristics with the other terms, put their relation forward. Because of these characteristics, while turning the complicated and difficult terms, the game has a positive and active role.