The development of the Internet and communication technology has revolutionarily changed the education contents and methods. Various governments and people with vision have promoted education to the highlight to determine the future of citizens in a nation.A teacher has to develop more creative teaching methods to teach new-generation students. Past research proved that cultivating students' creative thinking could significantly affect students' creativity and learning achievement. The approach of web-based era revolutionarily changed the media of creative thinking teaching. Applying design of experiment to the quasi-experimental research, total 186 universities and college students in Taiwan are preceded a 4-month teaching program in this study. The research findings show 1. positively remarkable effects of web-based creative thinking teaching on creativity, 2. positively notable effects of creativity on learning outcome, and 3. positively significant effects of web-based creative thinking teaching on learning outcome. At the end, suggestions for teachers' teaching methods are proposed, expecting to make up the theories related to web-based creative thinking teaching.