The purpose of the study was to examine the relationships among maladaptive perfectionism, self-compassion, and depressive symptoms in college students. It was hypothesized that self-compassion would mediate the relationship between maladaptive perfectionism and depressive symptoms, with maladaptive perfectionism related to lower levels of self-compassion, and lower levels of self-compassion related to greater endorsement of depressive symptoms. Results supported partial mediation, indicating that self-compassion partially accounts for the relationship between maladaptive perfectionism and depressive symptoms. Implications for practice and research are discussed.