A classroom response system (CRS) involves the use of remote devices allowing all students in a class to respond to questions displayed on a projection screen. A CRS instantly collects, tallies, and shows students' answers to a question on a classroom projection screen--a similar system used in the TV show "Who wants to be a millionaire" to collect audience responses. In this paper, the author proposed a comparable technology--Google Forms--that can be used in a computer lab and then studied gender differences in the relationship between the use of Google Forms and performance changes. Performance was measured by both the letter grades distribution and raw exam scores. The initial results suggested that the use of Google Form did not make any difference in the performances measured by the letter grades distribution. However, when the raw exam scores were compared with a covariate of calculus grades, the results suggest that the use of Google Forms resulted in improved performance. Further, the performance improvement of male students was greater than that of female students. Discussions and areas for future research are also presented.