ERIC Number: EJ1093629
Record Type: Journal
Publication Date: 2016
Abstractor: As Provided
Reference Count: 17
A Laboratory Exercise for Genotyping Two Human Single Nucleotide Polymorphisms
Fernando, James; Carlson, Bradley; LeBard, Timothy; McCarthy, Michael; Umali, Finianne; Ashton, Bryce; Rose, Ferrill F., Jr.
Journal of Biological Education, v50 n1 p73-85 2016
The dramatic decrease in the cost of sequencing a human genome is leading to an era in which a wide range of students will benefit from having an understanding of human genetic variation. Since over 90% of sequence variation between humans is in the form of single nucleotide polymorphisms (SNPs), a laboratory exercise has been devised in order to illustrate the importance of SNPs. Two separate SNPs are analysed, one of which has a significant effect on a person's phenotype and one which does not. The genotyping protocol is relatively inexpensive and uses standard molecular biology reagents and equipment.
Descriptors: Genetics, Science Laboratories, Science Instruction, Science Activities, Molecular Biology, Science Experiments, Laboratory Experiments, College Science, College Students, Science Tests
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Publication Type: Journal Articles; Reports - Research; Tests/Questionnaires
Education Level: Higher Education; Postsecondary Education
Authoring Institution: N/A
Identifiers - Location: Nebraska