ERIC Number: EJ1093192
Record Type: Journal
Publication Date: 2016-Apr
Abstractor: As Provided
Reference Count: 18
Assessment of Cognitive Outcome Measures in Teenagers with 15q13.3 Microdeletion Syndrome
Crutcher, Emeline; Ali, May; Harrison, John; Sovago, Judit; Gomez-Mancilla, Baltazar; Schaaf, Christian P.
Journal of Autism and Developmental Disorders, v46 n4 p1455-1463 Apr 2016
15q13.3 microdeletion syndrome causes a spectrum of cognitive disorders, including intellectual disability and autism. We aimed to determine if any or all of three cognitive testing systems (the KiTAP, CogState, and Stanford-Binet) are suitable for assessment of cognitive function in affected individuals. These three tests were administered to ten individuals with 15q13.3 microdeletion syndrome (14-18 years of age), and the results were analyzed to determine feasibility of use, potential for improvement, and internal consistency. It was determined that the KiTAP, CogState, and Stanford-Binet are valid tests of cognitive function in 15q13.3 microdeletion patients. Therefore, these tests may be considered for use as objective outcome measures in future clinical trials, assessing change in cognitive function over a period of pharmacological treatment.
Descriptors: Autism, Pervasive Developmental Disorders, Genetic Disorders, Adolescents, Cognitive Tests, Intellectual Disability, Intelligence Tests, Cognitive Ability, Test Reliability, Feasibility Studies, Improvement, Test Validity
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Authoring Institution: N/A
Identifiers - Assessments and Surveys: Stanford Binet Intelligence Scale