Adaptive teaching is an instructional approach where differences among learners are clearly recognized. For the last decade, our research team has studied literacy teachers' instructional adaptations in numerous classrooms in different regions of the United States. In this article, we share conclusions and insights from this longitudinal research. Specifically, we describe the characteristics of teachers who adapt their literacy instruction to support the individual needs of their students. Our aim is to support practicing teachers in their efforts to teach adaptively as they negotiate literacy instruction in today's diverse classrooms.