This study attempted to examine the influence of job stressors and organizational innovation climate on employees' innovative behavior. Data were obtained from 282 employees in 4 cities of China. Results indicated that the nature of stressors matters in predicting employees' idea generation. Specifically, stressors that employees tend to appraise as challenges were positively related to idea generation, whereas stressors that employees tend to appraise as hindrances were negatively related to idea generation. In addition, hindrance stressors moderated the relationship between organizational innovation climate and innovative behavior. The beneficial effect of organizational innovation climate on innovative behavior became weaker for idea implementation and totally disappeared for idea generation when confronting with high hindrance stressors. Implications of this study are also discussed.