There is little doubt that career experiences contribute to scientific achievement; however this relationship has yet to be thoroughly investigated in terms the effects on scientific creativity. In this study, a historiometric approach was used to examine 3 areas of adult career experiences common to scientific achievement. In doing so, prior theoretical work was used to identify career experiences relevant to scientific achievement, and 3 theoretical models were proposed to account for these experiences--adversity, collaborations, and work strategies. Biographies of eminent scientists were then content coded and analyzed. The results indicated that the adversity model did not predict scientific creativity. However, the work strategies model and, to some degree, the collaborations model showed some promise in understanding the development of creative potential in scientists. The nature of the significant relationships among the model components and scientific creativity are discussed in addition to their implications for the development of the creative potential of scientists.