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ERIC Number: EJ1087807
Record Type: Journal
Publication Date: 2015
Pages: 8
Abstractor: As Provided
Reference Count: N/A
ISBN: N/A
ISSN: ISSN-1470-8175
Pedagogical View of Model Metabolic Cycles
García-Herrero, Victor; Sillero, Antonio
Biochemistry and Molecular Biology Education, v43 n6 p468-475 Nov-Dec 2015
The main purpose of this study was to present a simplified view of model metabolic cycles. Although the models have been elaborated with the "Mathematica" Program, and using a system of differential equations, the main conclusions were presented in a rather intuitive way, easily understandable by students of general courses of Biochemistry, and without any need of mathematical support. A change in any kinetic constant (Km or Vmax) of only one enzyme affected the metabolic profile of all the substrates of the cycle. In addition, it is shown how an increase in the Km or a decrease in the Vmax values of any particular enzyme promoted an increase of its substrate; the contrary occurred decreasing the Km or increasing the Vmax values.
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A