Comparative literary studies characterize similarities and dissimilarities found in poetic works of two writers of different cultures. This study focuses on the use of allusions in poetry of John Milton particularly with reference to Paradise Lost and poetry of Persian Poet Hafiz Sherazi. Using allusions in poetry has been a common style of poets belonging to various cultures and languages as they add to the beauty and imagery of the poem. Yet it arises some difficulties and problems for the readers of the other culture and language. Being alien to a certain culture, the readers of the other language cannot understand the context and meaning of the reference in the form of allusions. Therefore the responsibility lies on the shoulders of the comparatists or the translators to explain and interpret these allusions for comprehension of the readers.