ERIC Number: EJ1082436
Record Type: Journal
Publication Date: 2015-Nov
Abstractor: As Provided
Reference Count: 29
Assessing Process Mass Intensity and Waste via an "aza"-Baylis-Hillman Reaction
Go´mez-Biagi, Rodolfo F.; Dicks, Andrew P.
Journal of Chemical Education, v92 n11 p1938-1942 Nov 2015
A synthetic procedure is outlined where upper-level undergraduate organic chemistry students perform a two-week, semimicroscale "aza"-Baylis-Hillman reaction to generate an allylic sulfonamide product. Students evaluate several green chemistry reaction metrics of industrial importance (process mass intensity (PMI), E factor, and reaction mass efficiency) and specifically learn the pivotal role that PMI plays in improving operational sustainability. Advantages and disadvantages of the various metrics are highlighted within the context of a multicomponent transformation eliciting current research activity.
Descriptors: Science Instruction, College Science, Undergraduate Study, Science Laboratories, Organic Chemistry, Hands on Science, Science Experiments, Laboratory Experiments, Scientific Concepts
Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: firstname.lastname@example.org; Web site: http://pubs.acs.org/jchemeduc
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education; Postsecondary Education
Authoring Institution: N/A