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ERIC Number: EJ1082436
Record Type: Journal
Publication Date: 2015-Nov
Pages: 5
Abstractor: As Provided
ISSN: ISSN-0021-9584
Assessing Process Mass Intensity and Waste via an "aza"-Baylis-Hillman Reaction
Go´mez-Biagi, Rodolfo F.; Dicks, Andrew P.
Journal of Chemical Education, v92 n11 p1938-1942 Nov 2015
A synthetic procedure is outlined where upper-level undergraduate organic chemistry students perform a two-week, semimicroscale "aza"-Baylis-Hillman reaction to generate an allylic sulfonamide product. Students evaluate several green chemistry reaction metrics of industrial importance (process mass intensity (PMI), E factor, and reaction mass efficiency) and specifically learn the pivotal role that PMI plays in improving operational sustainability. Advantages and disadvantages of the various metrics are highlighted within the context of a multicomponent transformation eliciting current research activity.
Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail:; Web site:
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education; Postsecondary Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A