The problem in this research is the lack of creative thinking skills of students. One of the learning models that is expected to enhance student's creative thinking skill is the local culture-based mathematical heuristic-KR learning model (LC-BMHLM). Heuristic-KR is a learning model which was introduced by Krulik and Rudnick (1995) that is the development of Polya's heuristic. This research aims to know the effectiveness of the LC-BMHLM model in enhancing creative thinking skills of students. The population in this research were students in a senior high school in Rantepao District with a sample size of 72 students. The sampling technique was cluster random sampling. Schools selected as a sample assigned one class as a class experiment who got LC-BMHLM model and one more class as a control class who got regular learning. The instruments used were the prior mathematical knowledge (PMK) test, and the creative thinking skills test (CTS). The data was analyzed using t-test, Mann-Whitney test, and two-way ANOVA. The results of this research show that LC-BMHLM model was effective in enhancing students' creative thinking skills. Students who have a high value of PMK have a high CTS, students who have middle and low PMK have a middle CTS, though both are classified as middle, but the post test average of those who have middle PMK are better than students who have low PMK.