The intent of this study is to assess the challenges and Opportunity of Basketball development of in Some Selected Regions Ethiopia. The research made Addis Ababa, Oromia, Gambella and South Nation Nationality and People Regional States as the sites of this study. Both qualitative and quantitative approaches particularly a descriptive survey were employed as they were found to be appropriate for answering the basic research questions. Instrument of data collection included questionnaire, interview and document analysis. Pertaining to the sample population for the study, Basketball Players, Coaches, Referees, Sport Science Scholars and Sport Administrators (N = 200) were involved. The result indicates that there are huge gap as regards to the development of basketball. According to the finding of the study, there are lack of trained human power, lack of sound policies and strategies of Basketball development. The result also revealed a shortage of budget, facilities, equipments and other necessary materials at the sample of Regional States. shortage of basketball competitions at various sex and age categories, Problems of communication and continuous material, logistic and moral support from Sport Commission and National Federation were identified be side. Furthermore the study revealed the talent identification and development were very weak and number of basketball clubs only limited to the capital of the country hence Addis Ababa City Administration is the only regions which have basketball clubs. Finally the finding of the study shows that these four Regions possess huge basketball talent and growth potentials. To this end National and Regional Sport commissions, Ethiopian Basketball Federation and other concerned sport authorities have to make all necessary provision urgently to develop and expand basketball sport, in order to produce talented and outstanding athletes both at regional and national level.