This study investigated the influence of marital stressors on role performance of married academic women of tertiary institutions in Cross River State. In order to accomplish the purpose of the study, two objectives and corresponding two hypotheses were postulated to guide the study. The survey research design was adopted in the study. A total of 421 women academics were drawn from the four tertiary institutions used. The instrument that was used in this study is a 61 items questionnaire tagged Influence of Marital Stressors on Role Performance Questionnaire (IMSRPQ). Five experts in Guidance and Counselling and Measurement and Evaluation were used to establish the face validity of the instrument. The reliability estimate for the instrument was 0.73. Multiple regression analysis was used for testing the hypotheses. The result of the study showed that marital stressors influenced the role performance of the married academic women in tertiary institutions in Cross River State and the influence was significant. Based on the above, recommendations were made that women academics should be encouraged to attend professional conferences, seminars and workshops in their discipline. Organizing professional seminars and workshop for women academics might be indirect ways of assisting them manage their stress, etc.