Teacher-student relationship and questioning strategies are extremely crucial elements in English teaching and learning. Questioning strategies can influence learners' emotional changes in classroom and the relationship between teachers & students. The affective factors play a very important role in language teaching & learning. Questioning strategy is a fine effective strategy in teacher-student interaction, and it benefits the construction of new teacher-student relationship. Based on the questionnaires concerning current survey of "teacher-student relationship" and "questioning strategies in English classroom", we get the conclusion that the current teacher-student relationship and the questioning situation are not optimistic in teaching English as a second language (ESL). Most of students desire the new, harmonious, democratic teacher-student relationship, and want to show a nice performance in English class, and hope to be questioned in a proper and respectful way. Meanwhile, the paper, based on the affective factors and construction of new teacher-student relationship, puts forward some questioning strategies for construction of new teacher-student relationship.