Undoubtedly, CD-ROM dictionaries assist in removing the fear of inadequacy in language usage and ameliorating the panic of being-on-the-spot especially with the rapid development of information technology. This research was conducted to find out whether there is a relationship between pre-service TESOL teachers' attitudes towards using CD-ROM dictionaries and certain criteria (perceived usefulness, perceived ease of use, functions and multimedia content). The theoretical framework for the study was drawn from TAM model. A modified questionnaire was utilised with employing a mixed-method approach using two sampling techniques (Purposive and Random) to pre-service TESOL teachers. The finding exposed a positive significant correlation between attitudes towards using CD-ROM dictionaries and criteria. A further finding exhibited that the CD-ROM dictionaries do assist learning the four main language skills (reading, writing, listening and speaking) and the subsidiary skills (grammar, punctuation and pronunciation).