ERIC Number: EJ1079339
Record Type: Journal
Publication Date: 2015-Oct
Abstractor: As Provided
Reference Count: 14
Improved Syntheses and Expanded Analyses of the Enantiomerically Enriched Chiral Cobalt Complexes Co(en)[subscript 3]I[subscript 3] and Co(diNOsar)Br[subscript 3]
McClellan, Michael J.; Cass, Marion E.
Journal of Chemical Education, v92 n10 p1766-1770 Oct 2015
This communication is a collection of additions and modifications to two previously published classic inorganic synthesis laboratory experiments. The experimental protocol for the synthesis and isolation of enantiomerically enriched ?- (or ?-)Co(en)[subscript 3]I[subscript 3] has been modified to increase reproducibility, yield, and enantiomeric excess. A computational component including molecular visualizations, model building, and energy minimization may be added to teach about the conformers that are formed as a result of ? and d twists of the ligands. Modification of a second experiment for the synthesis of a Sargeson encapsulation product (?-(or ?-)Co(diNOsar)- Br[subscript 3]) from enantiomerically enriched ?-(or ?-)Co(en)[subscript 3]I[subscript 3] includes advanced undergraduate analytical techniques including COSY, HMQC (or HETCOR), and NOESY NMR experiments, molecular visualizations, and CD spectroscopy for the characterization of products. Synthesis of a deuterated d[superscript 12]-Co(diNOsar)Br[subscript 3] (which facilitates NMR assignments) is also described.
Descriptors: Laboratory Experiments, Inorganic Chemistry, Synthesis, Undergraduate Students, Hands on Science, Computer Managed Instruction, Spectroscopy, Molecular Structure, Media Adaptation, Scientific Concepts, Scientific Methodology, Scientific Principles, Scientific Research
Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: email@example.com; Web site: http://pubs.acs.org/jchemeduc
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education; Postsecondary Education
Sponsor: National Science Foundation (NSF)
Authoring Institution: N/A
IES Grant or Contract Numbers: CHE1428752