The study investigated into the relationship between the quality of teachers and students' academic performance in Sekondi Takoradi Metropolitan Assembly (STMA) Junior High Schools. Descriptive survey design was used and the target population was Junior High School teachers and pupils in the metropolis. Five educational circuits in the metropolis were randomly selected for the conduct of the study. Stratified and systematic sampling techniques were used to sample participants and the sample size was 500. Questionnaire was the main instrument used for the data collection. Pearson Moment Correlation, ANOVA, means, percentages and standard deviations were used to analyse the data. The results of the study showed that even though the quality of teachers was high in terms of their academic and professional qualifications, it did not reflect much in the performance of the students.