This study was conducted with the participation of 31 pre-service science teachers. Participants were asked to develop various research questions on germination. The study aims to examine research questions on the subject germination from the perspective of scientific creativity. The research questions were examined using the fluency, science knowledge, flexibility, and originality dimensions of scientific creativity. The study thus provides an analysis of the research question developed by pre-service science teachers on germination from the perspective of scientific creativity. It was found that the research questions developed by pre-service science teachers on germination were very satisfactory in terms of fluency and science knowledge, but unsatisfactory in terms of flexibility and originality. This might be attributed to their lack of experience in creative thinking, making it difficult to see events from different and multiple perspectives.