Background: The Behaviour Problems Inventory-Short Form (BPI-S) is a spin-off of the BPI-01 that was empirically developed from a large BPI-01 data set. In this study, the reliability and factorial validity of the BPI-S was investigated for the first time on newly collected data from adults with intellectual disabilities. Methods: The sample consisted of 232 adults with intellectual disabilities who represented all levels of intellectual functioning. They were recruited at several day programs in the USA (n = 148) and the UK (n = 84). Results: We found acceptable reliability in terms of internal consistency, inter-rater agreement and test-retest reliability. Confirmatory factor analysis validated the three BPI-S subscale structure. Conclusions: We corroborated the factor structure underlying the three subscales and found the BPI-S to have adequate to good psychometric properties in a newly collected sample of adults with intellectual disabilities.