Business English in China has evolved into a degree programme from an ESP teaching programme in the past decades. The degree programme of Business English major intends to cultivate multi-skilled talents of foreign language to better satisfy the real needs of society and economy through curriculum design and teaching method innovation activities. This paper only focuses on reflecting into the mixed proportion of business knowledge courses and English language courses in the curriculum design of Business English major degree programmes at undergraduate and postgraduate levels. It concludes that the basic principle of Business English curriculum design in terms of mixture degree of business and English should be: maintaining 60-70% English language courses and 30-40% business knowledge courses, increasing business knowledge courses within the limit, and showing local features, etc. in order to better achieve the education target of such multi-skilled talents.