ERIC Number: EJ1074372
Record Type: Journal
Publication Date: 2015-Sep
Abstractor: As Provided
Reference Count: 12
Synthesis of 10-Ethyl Flavin: A Multistep Synthesis Organic Chemistry Laboratory Experiment for Upper-Division Undergraduate Students
Sichula, Vincent A.
Journal of Chemical Education, v92 n9 p1539-1542 Sep 2015
A multistep synthesis of 10-ethyl flavin was developed as an organic chemistry laboratory experiment for upper-division undergraduate students. Students synthesize 10-ethyl flavin as a bright yellow solid via a five-step sequence. The experiment introduces students to various hands-on experimental organic synthetic techniques, such as column chromatography, thin layer chromatography (TLC), extraction techniques, and characterizing intermediates and final products by IR and NMR spectroscopy. It also provides an opportunity for students to review important topics such as nucleophilic substitution reactions, hydrolysis of amides, condensation reactions, and reduction of aromatic nitro groups to amines.
Descriptors: Organic Chemistry, Science Instruction, Science Laboratories, Undergraduate Students, College Science, Science Experiments, Hands on Science, Spectroscopy, Laboratory Experiments
Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: firstname.lastname@example.org; Web site: http://pubs.acs.org/jchemeduc
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education; Postsecondary Education
Authoring Institution: N/A