While the leading edge between nursing and information provides an opportunity to expand the limitations of nursing knowledge and practice and creates new leadership roles for nurses, it also requires special competencies for safe and effective nursing practice. This study, therefore, assesses informatics competencies and examines the pedagogic and practical need for ICT in nursing education at Millikin University. Quantitative study using a survey design was found appropriate for this study because it allows a larger sample to be pulled from the undergraduate nursing students at Millikin University School of Nursing. All undergraduate nursing students are eligible to participate in the study. Overall, students reported greatest competencies with respect to computer literacy, having positive attitudes toward ICT uses, able to assess ICT in an informed manner, effectively searching on-line information sources and understand the application of nursing workload data to clinical productivity management.