The study sought to establish the influence of ICT competence on lecturers' job efficacy in two universities in Nigeria. The sample of the study consisted of 500 university teachers randomly sampled from a population of 1,795 teachers. The results of the study revealed that male and female lecturers did not differ significantly in their level of ICT competence. Lecturers with high ICT competence were found to be more effective in classroom instruction, research/publications, and communication and record-keeping than those with moderate and low ICT competence. The findings of this study revealed that the level of ICT competence of lecturers significantly enhanced their job efficacy. Premised on these findings, it was recommended that lecturers should be motivated to develop their ICT competence as this has been found to improve job efficacy for high productivity. University management should encourage lecturers to participate in ICT training programmes and ICT facilities should be provided in lecturers' offices to enhance their job efficacy.