The study aimed at investigating the relationship between writing anxiety and writing self-efficacy in English for special education Arab learners of English. It also investigated the use of writing anxiety scores as a predictor of writing self-efficacy. In addition, it explored differences between males and females in both writing anxiety and writing self-efficacy in English. The sample of the study consisted of 90 intermediate school students in the state of Kuwait (47 males and 43 females); the mean age was 8.67 years and the standard deviation was 2.4 years. The descriptive research design was adopted in the study. The researchers used writing anxiety scale, writing self-efficacy scale and an achievement test in English writing skills. Results of the study showed that there is a positive relationship between students' writing anxiety and writing self-efficacy for male students and the overall sample while no relationship was detected among these variables for female students. In addition, results revealed that writing anxiety scores could be used as a predictor of students' writing self-efficacy in English for male students and the overall sample of the study whereas writing anxiety scores could not be used as a predictor of writing self-efficacy for female students. It was found that there were no statistically significant differences between male and female students in their scores of writing anxiety and writing self-efficacy in English Language.