This study aimed at identifying the challenges facing women academic leadership in secondary schools of Irbid Educational Area. A random sample of 187 female leaders were chosen. They responded to a 49-item questionnaire prepared by the researcher. The items were distributed into four domains: organizational, personal, social and physical challenges. The study concluded that the women academic leaders are facing challenges between medium and high levels. In addition, there is no difference attributed to the job position in all domains, except for the physical challenges in favor for the principals. There were differences attributed to the academic qualification in all the domains in favor of those who hold BA degrees or higher, except for the organizational challenges domain. Finally, there were no differences related to the years of experience in all domains. The study recommended setting up developmental programs for the women's academic leaders.