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ERIC Number: EJ1068505
Record Type: Journal
Publication Date: 2015-Aug
Pages: 6
Abstractor: As Provided
Reference Count: 23
ISBN: N/A
ISSN: ISSN-1362-3613
Phenotypic Differences in Individuals with Autism Spectrum Disorder Born Preterm and at Term Gestation
Bowers, Katherine; Wink, Logan K.; Pottenger, Amy; McDougle, Christopher J.; Erickson, Craig
Autism: The International Journal of Research and Practice, v19 n6 p758-763 Aug 2015
The objective of the study was to characterize the phenotype of males and females with autism spectrum disorder born preterm versus those born at term. Descriptive statistical analyses identified differences between male and female autism spectrum disorder subjects born preterm compared to term for several phenotypic characteristics and comorbidities. Of the 115 (13.0% of 883) born preterm, a greater percentage of males had sleep apnea (13.8% vs 2.5%, p?<?0.0001), seizure disorders (17.0% vs 8.5%, p?=?0.01), and attention-deficit/hyperactivity disorder (14.9% vs 6.6%, p?=?0.005). Females born preterm were more likely to be nonverbal (22.2% vs 4.6%, p?=?0.001). In summary, phenotypic differences were observed, especially among males. The results may have implications for understanding the underpinnings of a subset of individuals with autism spectrum disorder and contribute to the development of focused treatments for autism spectrum disorder among children born preterm.
SAGE Publications. 2455 Teller Road, Thousand Oaks, CA 91320. Tel: 800-818-7243; Tel: 805-499-9774; Fax: 800-583-2665; e-mail: journals@sagepub.com; Web site: http://sagepub.com
Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A