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ERIC Number: EJ1067964
Record Type: Journal
Publication Date: 2015-Jul
Pages: 5
Abstractor: As Provided
Reference Count: N/A
ISBN: N/A
ISSN: ISSN-1072-0502
Pretrial Hippocampal ?-State Differentiates Single-Unit Response Profiles during Rabbit Trace Eyeblink Conditioning
Cicchese, Joseph J.; Darling, Ryan D.; Berry, Stephen D.
Learning & Memory, v22 n7 p318-322 Jul 2015
Eyeblink conditioning given in the explicit presence of hippocampal ? results in accelerated learning and enhanced multiple-unit responses, with slower learning and suppression of unit activity under non-? conditions. Recordings from putative pyramidal cells during ?-contingent training show that pretrial ?-state is linked to the probability of firing increases versus decreases rather than to the magnitude of such responses. These findings suggest that the learning facilitation during ? may be due to the recruitment of additional neurons that increase their firing rate during trials.
Cold Spring Harbor Laboratory Press. 500 Sunnyside Boulevard, Woodbury, NY 11797-2924. Tel: 800-843-4388; Tel: 516-367-8800; Fax: 516-422-4097; e-mail: cshpres@cshl.edu; Web site: http://www.learnmem.org/
Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A