Purpose: The larynx has a dual role in the regulation of gas flow into and out of the lungs while also establishing resistance required for vocal fold vibration. This study assessed reciprocal relations between phonatory functions--specifically, phonatory laryngeal airway resistance (R[subscript law])--and respiratory homeostasis during states of ventilatory gas perturbations. Method: Twenty-four healthy women performed phonatory tasks while exposed to induced hypercapnia (high CO[subscript 2]), hypocapnia (low CO[subscript 2]), and normal breathing (eupnea). Effects of gas perturbations on R[subscript law] were investigated as were the reciprocal effects of R[subscript law] modulations on respiratory homeostasis. Results: R[subscript law] remained stable despite manipulations of inspired gas concentrations. In contrast, end-tidal CO[subscript 2] levels increased significantly during all phonatory tasks. Thus, for the conditions tested, R[subscript law] did not adjust to accommodate ventilatory needs as predicted. Rather, stable R[subscript law] was spontaneously accomplished at the cost of those needs. Conclusions: Findings provide support for a theory of regulation wherein R[subscript law] may be a control parameter in phonation. Results also provide insight into the influence of phonation on respiration. The work sets the foundation for future studies on laryngeal function during phonation in individuals with lower airway disease and other patient populations.