An approach to motivation in the contemporary world of work is the implementation of Quality-of-Worklife (QWL) programmes, which is aimed at easing the pressures faced at work by employees. Quality-of-Worklife is a philosophy of improving productivity by providing workers with the opportunities required to put in their best at work, without jeopardizing their personal self improvement and responsibilities at home. The effectiveness of organisational factors and QWL programmes in the Nigerian tertiary institutions is under-researched. This study, therefore, investigates the organisational pressure on Quality-of-Worklife of women in tertiary institutions in Lagos State, Nigeria. It is a survey of the ex-post facto type. 3,640 senior cadre women working in the four purposively selected degree awarding institutions in Lagos State (University of Lagos, Lagos University Teaching Hospital, Lagos State University and Lagos State University Teaching Hospital) and their managers formed the population. Out of these, 1000 women and 19 managers were randomly selected as sample. A QWL survey and structured interview made up the instrument. Four hypotheses were tested at 0.05 significance level. There were significant differences among the institutions in the compliance to International Labour Organisation (ILO) conventions and in the Quality-of-Worklife of their women workers. Moreover, there were significant relationships between QWL and sources of pressure and QWL and organisational pressure. Factors such as salary, health-care benefit, day-care services, recognition, workload and others, influenced QWL of women. Government and management committees of the tertiary institutions should ensure the reduction of organisational pressure and promote high QWL of women workers, in other to improve on their productivity and promote organisational growth.