The study was intended to compare the quality of teaching learning process in the faculty of social science and science at University of Sargodha. This study was descriptive and quantitative in nature. The objectives of the study were to compare the quality of teaching learning process in the faculty of social science and science at University of Sargodha. Respondent, department and gender wise comparison was also done a sample of 92 students studying in post graduate programs and 30 teachers teaching to post graduate programs were taken from five social sciences and five science departments for data collection. Convenient sampling technique was used to select the sample. A questionnaire was developed and Pilot study was conducted to find out the reliability of the questionnaire. The reliability of the questionnaire was found to be 0.794. The results of the study proved that there is no significant difference between the quality of teaching learning process in Science and Social Science departments at University of Sargodha. It was also concluded that there is a significant difference between teachers and students responses about the quality of teaching learning process. The findings will help the teachers to improve their teaching and instructional plans. The findings of this study will be significant to the faculties of science and social science to improve their learning environment.