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ERIC Number: EJ1062657
Record Type: Journal
Publication Date: 2015-Jun
Pages: 17
Abstractor: As Provided
Reference Count: 86
ISSN: ISSN-0162-3257
Typical and Atypical Neurodevelopment for Face Specialization: An fMRI Study
Joseph, Jane E.; Zhu, Xun; Gundran, Andrew; Davies, Faraday; Clark, Jonathan D.; Ruble, Lisa; Glaser, Paul; Bhatt, Ramesh S.
Journal of Autism and Developmental Disorders, v45 n6 p1725-1741 Jun 2015
Individuals with autism spectrum disorder (ASD) and their relatives process faces differently from typically developed (TD) individuals. In an fMRI face-viewing task, TD and undiagnosed sibling (SIB) children (5-18 years) showed face specialization in the right amygdala and ventromedial prefrontal cortex, with left fusiform and right amygdala face specialization increasing with age in TD subjects. SIBs showed extensive antero-medial temporal lobe activation for faces that was not present in any other group, suggesting a potential compensatory mechanism. In ASD, face specialization was minimal but increased with age in the right fusiform and decreased with age in the left amygdala, suggesting atypical development of a frontal-amygdala-fusiform system which is strongly linked to detecting salience and processing facial information.
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Publication Type: Journal Articles; Reports - Research
Education Level: Elementary Secondary Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A