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ERIC Number: EJ1062654
Record Type: Journal
Publication Date: 2015-Jun
Pages: 10
Abstractor: As Provided
Reference Count: 46
ISSN: ISSN-0162-3257
Maternal Smoking and Autism Spectrum Disorder: A Meta-Analysis
Rosen, Brittany N.; Lee, Brian K.; Lee, Nora L.; Yang, Yunwen; Burstyn, Igor
Journal of Autism and Developmental Disorders, v45 n6 p1689-1698 Jun 2015
We conducted a meta-analysis of 15 studies on maternal prenatal smoking and ASD risk in offspring. Using a random-effects model, we found no evidence of an association (summary OR 1.02, 95% CI 0.93-1.12). Stratifying by study design, birth year, type of healthcare system, and adjustment for socioeconomic status or psychiatric history did not alter the findings. There was evidence that ascertaining exposure at the time of birth produced a lower summary OR than when this information was gathered after birth. There was no evidence of publication bias. Non-differential exposure misclassification was shown to have the potential for negligible influence on the results. We found no evidence to support a measurable association between maternal prenatal smoking and ASD in offspring.
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Publication Type: Journal Articles; Information Analyses; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A