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ERIC Number: EJ1062296
Record Type: Journal
Publication Date: 2015-Apr
Pages: 5
Abstractor: As Provided
Reference Count: 27
ISSN: ISSN-0021-9584
Student-Fabricated Microfluidic Devices as Flow Reactors for Organic and Inorganic Synthesis
Feng, Z. Vivian; Edelman, Kate R.; Swanson, Benjamin P.
Journal of Chemical Education, v92 n4 p723-727 Apr 2015
Flow synthesis in microfluidic devices has been rapidly adapted in the pharmaceutical industry and in many research laboratories. Yet, the cost of commercial flow reactors is a major factor limiting the dissemination of this technology in the undergraduate curriculum. Here, we present a laboratory activity where students design and fabricate homemade microfluidic flow reactors using thermoplastic molds and soft lithographic methods, and conduct inorganic syntheses of magnetite particles and gold-citrate nanoparticles, as well as a two-step organic synthesis of azo dyes. The success of these reactions can be quickly assessed by colors or physical characteristics, which makes optimizations of reactor designs and reaction conditions possible on-the-spot. The activity also successfully integrates some important concepts in chemical engineering, organic and inorganic synthesis, nanomaterial chemistry, and analytical chemistry.
Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail:; Web site:
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education; Postsecondary Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A