The teaching of research methods is common across multiple fields in the social and educational sciences for establishing evidence-based practices and furthering the knowledge base through scholarship. Yet, specific to mixed methods, scant information exists as to how to approach teaching complex concepts for meaningful learning experiences. Thus, the purpose of this mixed research study was to examine strategies used by selected U.S.-based leading mixed methodologists in mixed research courses as related to significant learning goals for course design. In addition, we examined the extent that their philosophical stances influenced teaching and course objectives for student learning. Participants were 12 leading mixed methodologists who were instructors of mixed research courses from various institutions representing multiple conceptual stances applicable to the teaching of mixed research. Instructional practices are presented for instructors to consider when designing and teaching mixed research and general research methodology courses across disciplines.