Today's NetGen students require more multimedia and interactive learning environments and greater participation than previous generations. Personal response devices (PRDs, sometimes called Audience Response Devices or ARDs, better known as clickers) show promise in helping to meet that need. This article explores the literature of PRDs to develop propositions about the impact of PRDs on learning in large introductory business classes (e.g., Principles of Marketing, Introduction to Supply Chain Management, Organizational Behavior, etc.). We report on two exploratory studies utilizing PRDs and discuss recommendations and observations on the use of PRDs.