Models of bilingual reading such as Bilingual Interactive Activation Plus (Dijkstra & van Heuven, 2002) do not predict a central role for domain-general executive control during bilingual reading, in contrast with bilingual models from other domains, such as production (e.g., the Inhibitory Control Model; Green, 1998). We thus investigated whether individual differences among bilinguals in domain-general executive control modulate cross-language activation during L2 sentence reading, over and above other factors such as L2 proficiency. Fifty French-English bilinguals read L2-English sentences while their eye movements were recorded, and they subsequently completed a battery of executive control and L2 proficiency tasks. High- and low-constraint sentences contained interlingual homographs ("chat" = "casual conversation" in English, "a cat" in French), cognates ("piano" in English and French), or L2-specific control words. The results showed that greater executive control among bilinguals but not L2 proficiency reduced cross-language activation in terms of interlingual homograph interference. In contrast, increased L2 proficiency but not executive control reduced cross-language activation in terms of cognate facilitation. These results suggest that models of bilingual reading must incorporate mechanisms by which domain-general executive control can alter the earliest stages of bilingual lexical activation.