Human sexuality courses are common across many college/university campuses. The methods of instruction typically encourage discussion to increase knowledge and critical thinking about self, relationships, and professional pathways. However, often the pedagogical practices do not include methods to draw out students with a range of personalities, backgrounds, and opinions. This is particularly challenging given the nature of the subject matter. The following discusses strategies employed to engage a variety of students through small discussion groups, survey response and backchannel technologies, and guided notes. Student feedback is included to illustrate perceived effectiveness.