Institutions of higher learning have struggled to retain incoming freshmen, especially Hispanic students, who historically face greater challenges to succeed. The purpose of this mixed-methods study was to investigate the relationship between resiliency, self-efficacy, and persistence of college seniors with an emphasis on first- and continued-generation Hispanic students. An examination of how retention factors have supported Hispanic college seniors was explored through qualitative interviews. Implications of this research provide insight to college, career, school, and community counselors working with prospective Hispanic students. Counselors are likely to address and support the needs of first- and continued-generation Hispanic students while contributing to the improvement of university programs. An emphasis on strategies to increase the number of Hispanic college graduates must include commitment at all levels of campus communities. Such emphasis will be advantageous to college and university counseling centers as they work with this particular population.